3-methyl-5-phenylisoxazole-4-carboxylic acid

3-methyl-5-phenylisoxazole-4-carboxylic acid - Names and Identifiers

Name	3-methyl-5-phenyl-4-isoxazolecarboxylic acid
Synonyms	AKOS PAO-1632 RARECHEM AL BE 1293 (4-Carboxy-3-methylisoxazol-5-yl)benzene 3-methyl-5-phenyl-4-isoxazolecarboxylic acid 3-METHYL-5-PHENYLISOXAZOLE-4-CARBOXYLIC ACID 3-methyl-5-phenylisoxazole-4-carboxylic acid 3-METHYL-5-PHENYL-4-ISOXAZOLECARBOXYLIC ACID 4-Isoxazolecarboxylic acid, 3-Methyl-5-phenyl-
CAS	17153-21-8
InChI	InChI=1/C11H9NO3/c1-7-9(11(13)14)10(15-12-7)8-5-3-2-4-6-8/h2-6H,1H3,(H,13,14)

3-methyl-5-phenylisoxazole-4-carboxylic acid - Physico-chemical Properties

Molecular Formula	C11H9NO3
Molar Mass	203.19
Density	1.273±0.06 g/cm3(Predicted)
Melting Point	189℃
Boling Point	362.1±37.0 °C(Predicted)
Flash Point	172.779°C
Vapor Presure	0mmHg at 25°C
pKa	2.17±0.32(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.579

3-methyl-5-phenylisoxazole-4-carboxylic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection
Hazard Note	Irritant

3-methyl-5-phenylisoxazole-4-carboxylic acid - Introduction

acid is an organic compound with the chemical formula C12H10N2O2.

Nature:
-Appearance: acid is a white crystalline solid.
-Melting point: about 165-170 ℃.
-Solubility: Soluble in some organic solvents, such as ethyl acetate, chloroform, etc.
-Chemical properties: The compound can undergo electrophilic substitution, nucleophilic substitution, and ring-closing reactions in some reactions.

Use:
-acryoid is often used as a synthetic intermediate of a raw material for antiepileptic drugs in the medical field. It can be used to synthesize drugs such as phenobarbital.
-The compound can also be used to synthesize other organic compounds, such as pesticides, dyes, etc.

Method:
The preparation of-aryl acid can be carried out by the method of phenyl-substituted isoxazole carboxylic acid. A common synthetic method is the co-thermal reaction of 2-methylbenzoic acid and ethyl formate with sulfuric acid to give forniacidazole.

Safety Information:
-the acid is an organic compound and care should be taken to prevent inhalation, skin contact and ingestion. Wear suitable personal protective equipment such as gloves, goggles and protective clothing during operation.
-During storage and transportation, it should be kept in a cool, well-ventilated place, and away from substances such as fire and oxidants.

Last Update：2024-04-09 02:00:43